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      1. 產品資料

        Margatoxin Kv1.3 selective blocker

        如果您對該產品感興趣的話,可以
        產品名稱: Margatoxin Kv1.3 selective blocker
        產品型號: 08MAG001-00100
        產品展商: 其他品牌
        產品文檔: 無相關文檔

        簡單介紹


        Margatoxin Kv1.3 selective blocker  的詳細介紹
        Margatoxin Kv1.3 selective blocker Margatoxin (MgTx) is a component of the venom of Scorpio Centruroides margaritatus. Margatoxin preferentially inhibits voltage-dependent potassium channels Kv1.3 with an IC50 value around 50 pM (20 fold more potent than Charybdotoxin) and irreversibly inhibits the proliferation response of human T-cells at 20 μM concentration. Margatoxin is known to be less potent on Kv1.3 expressed in Xenopus Oocytes (IC50 around 1 nM). Margatoxin was also described to be a potent inhibitor of human vascular smooth muscle cell migration with an IC50 of 85 pM.
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